Dorsal root ganglia neurite outgrowth measured as a function of changes in microelectrode array resistance
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Dorsal root ganglia neurite outgrowth measured as a function of changes in microelectrode array resistance
Current research in prosthetic device design aims to mimic natural movements using a feedback system that connects to the patient's own nerves to control the device. The first step in using neurons to control motion is to make and maintain contact between neurons and the feedback sensors. Therefore, the goal of this project was to determine if changes in electrode resistance could be detected w...
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neurite outgrowth from dorsal root ganglion (drg) explants is a method of evaluating neurotrophic activity of growth factors. when complete medium containing collagen was supplemented with nerve growth factor (ngf) drg outgrowth was observed after 18 h. in the absence of ngf and in the presence of collagen, the drg outgrowth took place after 72 h. in wells not supplemented with collagen gel in ...
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Activin A, a member of the transforming growth factor β (TGFβ) superfamily, plays an essential role in neuron survival as a neurotrophic and neuroprotective factor in the central nervous system. However, the effects and mechanisms of action of activin A on the neurite outgrowth of dorsal root ganglia (DRG) remain unclear. In the present study, we found that activin A is expressed in DRG collect...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0175550